The accident took place at around 10 PM when the driver of the passenger bus lost control over steering near Hajaridanga under Bissam Cuttack police limits in the district. The bus was on its way to Bhubaneswar carrying at least 30 passengers, sources said.
Soon after the mishap, locals rescued the passengers and alerted the local police and fire personnel in this regard following which the injured were rushed to a nearby hospital.
Two people including a driver of the vehicle succumbed to their injuries at the hospital.
District Collector Pramod Kumar Behera also reached the spot to take stock of the situation.