He also received critics' accolades for his role of Dr Maiti in the Vidya Balan and Arjun Rampal starrer, 'Kahaani 2: Durga Rani Singh'.
Mukherjee was hospitalised on August 22 following a lung infection. His condition started deteriorating from Sunday and he had to be given ventilator support.
He was tested Covid-19 positive twice in the last two years.
Besides acting, Mukherjee was also a practising tax consultant.
He is survived by his wife, son and daughter.
Mukherjee was born on August 11, 1946 and after graduating from City College in Kolkata, he also received a degree in law.
He had been attracted to acting since his college days.
Besides taking drama lessons, he was actively associated with a number of theatre academies.
He started his acting career on stage, where he was noticed by Satyajit Ray, who featured him as Somnath in his iconic movie 'Jana Aranya'.